Magnesium oxide is a mineral supplement used to treat magnesium deficiency and is available over the counter under brand names such as Mag-Ox, Uro-Mag, and Mag-Caps. It is also used to treat constipation, indigestion, high blood pressure during pregnancy, irregular heartbeat, asthma, and pain caused by nerve damage associated with cancer, among other things. While magnesium needs are increased during pregnancy, the safety of magnesium oxide during pregnancy has not been established. Controlled studies in pregnant women show no evidence of fetal risk, but there are no controlled data in human pregnancy. Oral magnesium supplements do not appear to help with leg cramps during pregnancy, and the National Institute for Health and Care Excellence (NICE) does not recommend using magnesium solely for the prevention of hypertensive disorders in pregnancy.
Characteristics | Values |
---|---|
Safety | Safety has not been established during pregnancy. |
US FDA pregnancy category | Not assigned |
Magnesium needs during pregnancy | Increased |
Oral magnesium supplements' effect on leg cramps during pregnancy | Do not appear to help |
National Institute for Health and Care Excellence's recommendation on magnesium | Does not recommend using magnesium solely for prevention of hypertensive disorders in pregnancy |
Magnesium oxide's effect on newborn hyperbilirubinemia and hospitalization in gestational diabetes | May lower the incidence |
Magnesium oxide's distribution in breast milk | Yes |
Recommended daily intake of magnesium oxide for pregnant females aged 19-30 years | 350 mg/day orally |
Recommended daily intake of magnesium oxide for pregnant females over 31 years | 360 mg/day orally |
Magnesium oxide's pregnancy category | A |
Controlled studies in pregnant women showing evidence of fetal risk | No |
What You'll Learn
Magnesium oxide is generally considered safe during pregnancy
The recommended daily intake of magnesium oxide for pregnant women aged 19-30 is 350 mg/day orally, and for those over 31, it is 360 mg/day orally. Magnesium is a vital mineral for maintaining bone structure, and it is recommended that women consume 280 mg of magnesium per day, with increased intake during pregnancy.
Magnesium oxide is also beneficial for fetal health. Studies have shown that magnesium supplementation during pregnancy may reduce the risk of fetal growth restriction and preeclampsia, as well as increase birth weight. Additionally, magnesium citrate, a form of magnesium, can aid in calcium absorption, which is essential for fetal bone growth and development.
However, it is important to consult a doctor before taking magnesium oxide during pregnancy, as it can produce certain side effects, and there may be interactions with other medications.
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It is used to treat constipation, indigestion, and high blood pressure
Magnesium oxide is an over-the-counter medication that can be used to treat constipation, indigestion, and high blood pressure during pregnancy. It is deemed generally safe to use during pregnancy, with controlled studies showing no evidence of fetal risk. However, it is always recommended to consult a doctor before taking any medication while pregnant.
Constipation
Constipation is a common issue during pregnancy, and magnesium oxide is a saline laxative that can help relieve this issue. It works by drawing water from the intestines through osmosis, making it easier to pass stools. It is important to note that magnesium oxide should be used as a last resort for constipation treatment during pregnancy and only under medical supervision.
Indigestion
Magnesium oxide can also be used to treat indigestion, as it helps neutralise stomach acid and relieve stomach upset. It is often recommended to take magnesium supplements with meals to reduce stomach irritation.
High Blood Pressure
Magnesium oxide can be effective in treating high blood pressure during pregnancy, specifically pre-eclampsia and eclampsia. It helps to regulate blood pressure and maintain electrical potentials in nerve and muscle membranes.
While magnesium oxide is generally safe during pregnancy, it is important to follow the recommended dosage. For pregnant women aged 19-30, the recommended daily oral intake of elemental magnesium is 350 mg, while for those over 31, it is 360 mg. It is also important to note that magnesium oxide may interact with certain drugs, so it is crucial to consult a doctor or pharmacist before taking it.
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Magnesium is important for bone structure
Magnesium is an essential mineral for the human body and plays a vital role in maintaining normal bone structure. About 50-60% of total magnesium in the body is stored in the bones, with the rest present in the intracellular compartments and extracellular fluids.
Magnesium is a cofactor for vitamin D synthesis and activation, which in turn increases intestinal absorption of magnesium and helps maintain bone health. A deficiency in magnesium can affect bone health directly by reducing bone stiffness and decreasing osteoblasts (bone-forming cells) while increasing osteoclasts (bone-resorbing cells). It can also impact bone health indirectly by interfering with parathyroid hormone and vitamin D, as well as promoting inflammation and oxidative stress, which can lead to bone loss.
Several studies have shown a correlation between magnesium intake and bone mineral density. For example, a study of postmenopausal women found that those with osteoporosis had significantly lower serum magnesium levels than healthy women. Another study of older adults found a positive association between higher magnesium intake and higher hip and femoral neck bone mineral density.
Magnesium oxide is a commonly available magnesium supplement. While magnesium oxide is generally considered safe during pregnancy, it is always recommended to consult a healthcare professional before taking any supplements during pregnancy.
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Magnesium supplements are needed if magnesium levels are too low
Magnesium is a mineral that is important for normal bone structure in the body. People get magnesium from their diet, but sometimes magnesium supplements are needed if magnesium levels are too low. Dietary intake of magnesium may be low, particularly among women. Magnesium deficiency is also not uncommon among African Americans and the elderly. Low magnesium levels in the body have been linked to diseases such as osteoporosis, high blood pressure, clogged arteries, hereditary heart disease, diabetes, and stroke.
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Magnesium oxide is distributed in breast milk
Small amounts of magnesium are excreted in breast milk, with 50 to 90% of magnesium being absorbed. Urinary excretion of magnesium decreases and bone resorption increases during lactation. Maternal magnesium supplementation is not expected to affect the infant's serum magnesium levels. The recommended daily intake of magnesium oxide for pregnant women is 350-400 mg/day of elemental magnesium. During breastfeeding, this amount is lowered to 310-360 mg/day of elemental magnesium.
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Frequently asked questions
The use of magnesium oxide during pregnancy is generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk. However, safety has not been established during pregnancy and there are no controlled data in human pregnancy. It is recommended that you consult your doctor before taking any medication during pregnancy.
The recommended daily intake of magnesium oxide for pregnant women aged 19-30 is 350 mg/day orally. For pregnant women over 31, the recommended daily intake is 360 mg/day orally.
Common side effects of Mag Ox include diarrhoea with excessive dose and gastrointestinal irritation.